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Skiptomainnavigation Skiptosearch Skiptomaincontent Kidneydisease:Improvingglobaloutcomes(KDIGO)CKDworkgroup.KDIGO2012clinicalpracticeguidelinefortheevaluationandmanagementofchronickidneydisease AdeeraLevin,PaulE.Stevens,RudyW.Bilous,JosefCoresh,AngelL.M.DeFrancisco,PaulE.DeJong,KathrynE.Griffith,BrendaR.Hemmelgarn,KunitoshiIseki,EdmundJ.Lamb,AndrewS.Levey,MiguelC.Riella,MichaelG.Shlipak,HaiyanWang,ColinT.White,ChristopherG.Winearls BloombergSchoolofPublicHealth Researchoutput:Contributiontojournal›Editorial›peer-review Overview Fingerprint Abstract TheKidneyDisease:ImprovingGlobalOutcomes(KDIGO)2012ClinicalPracticeGuidelinefortheEvaluationandManagementofChronicKidneyDisease(CKD)servestoupdatethe2002KDOQIClinicalPracticeGuidelinesforChronicKidneyDisease:Evaluation,Classification,andStratificationfollowingadecadeoffocusedresearchandclinicalpracticeinCKD.Thedocumentaimstoprovidestate-of-the-artguidanceontheevaluation,managementandtreatmentforallpatientswithCKD.Specifically,theguidelineretainsthedefinitionofCKDbutpresentsanenhancedclassificationframeworkforCKD;elaboratesontheidentificationandprognosisofCKD;discussesthemanagementofprogressionandcomplicationsofCKD;andexpandsonthecontinuumofCKDcare:timingofspecialistreferral,ongoingmanagementofpeoplewithprogressiveCKD,timingoftheinitiationofdialysis,andfinallytheimplementationofatreatmentprogramwhichincludescomprehensiveconservativemanagement.Thedevelopmentoftheguidelinefollowedanexplicitprocessofevidencereviewandappraisal.Treatmentapproachesareaddressedineachchapterandguidelinerecommendationsarebasedonsystematicreviewsofrelevanttrials.Practicalcommentsorstatementswhichserveaseducationalpurposesareungraded,butincludedasimportantinformationforthereadership.AppraisalofthequalityoftheevidenceandthestrengthofrecommendationsfollowedtheGRADEapproach.Ongoingareasofcontroversies,limitationsoftheevidence,andinternationalrelevancearediscussedandadditionalsuggestionsareprovidedforfutureresearch. OriginallanguageEnglish(US)Pages(from-to)1-150Numberofpages150JournalKidneyInternationalSupplementsVolume3Issuenumber1DOIshttps://doi.org/10.1038/kisup.2012.73StatePublished-Jan12013 KeywordsAlbuminuriaChronickidneydiseaseClassificationClinicalpracticeguidelineEvidence-basedrecommendationGFRGlomerularfiltrationrateKDIGOProteinuriaSystematicreviewASJCScopussubjectareasNephrology AccesstoDocument 10.1038/kisup.2012.73 Otherfilesandlinks LinktopublicationinScopusLinktothecitationsinScopus PracticeManagement Medicine&LifeSciences 100% KidneyDiseases Medicine&LifeSciences 87% PracticeGuidelines Medicine&LifeSciences 78% ChronicRenalInsufficiency Medicine&LifeSciences 76% Guidelines Medicine&LifeSciences 16% DiseaseManagement Medicine&LifeSciences 8% ConservativeTreatment Medicine&LifeSciences 7% Dialysis Medicine&LifeSciences 7% Citethis APA Standard Harvard Vancouver Author BIBTEX RIS Levin,A.,Stevens,P.E.,Bilous,R.W.,Coresh,J.,DeFrancisco,A.L.M.,DeJong,P.E.,Griffith,K.E.,Hemmelgarn,B.R.,Iseki,K.,Lamb,E.J.,Levey,A.S.,Riella,M.C.,Shlipak,M.G.,Wang,H.,White,C.T.,&Winearls,C.G.(2013).Kidneydisease:Improvingglobaloutcomes(KDIGO)CKDworkgroup.KDIGO2012clinicalpracticeguidelinefortheevaluationandmanagementofchronickidneydisease.KidneyInternationalSupplements,3(1),1-150.https://doi.org/10.1038/kisup.2012.73 Kidneydisease:Improvingglobaloutcomes(KDIGO)CKDworkgroup.KDIGO2012clinicalpracticeguidelinefortheevaluationandmanagementofchronickidneydisease./Levin,Adeera;Stevens,PaulE.;Bilous,RudyW.etal.In:KidneyInternationalSupplements,Vol.3,No.1,01.01.2013,p.1-150.Researchoutput:Contributiontojournal›Editorial›peer-review Levin,A,Stevens,PE,Bilous,RW,Coresh,J,DeFrancisco,ALM,DeJong,PE,Griffith,KE,Hemmelgarn,BR,Iseki,K,Lamb,EJ,Levey,AS,Riella,MC,Shlipak,MG,Wang,H,White,CT&Winearls,CG2013,'Kidneydisease:Improvingglobaloutcomes(KDIGO)CKDworkgroup.KDIGO2012clinicalpracticeguidelinefortheevaluationandmanagementofchronickidneydisease',KidneyInternationalSupplements,vol.3,no.1,pp.1-150.https://doi.org/10.1038/kisup.2012.73 LevinA,StevensPE,BilousRW,CoreshJ,DeFranciscoALM,DeJongPEetal.Kidneydisease:Improvingglobaloutcomes(KDIGO)CKDworkgroup.KDIGO2012clinicalpracticeguidelinefortheevaluationandmanagementofchronickidneydisease.KidneyInternationalSupplements.2013Jan1;3(1):1-150.https://doi.org/10.1038/kisup.2012.73 Levin,Adeera;Stevens,PaulE.;Bilous,RudyW.etal./Kidneydisease:Improvingglobaloutcomes(KDIGO)CKDworkgroup.KDIGO2012clinicalpracticeguidelinefortheevaluationandmanagementofchronickidneydisease.In:KidneyInternationalSupplements.2013;Vol.3,No.1.pp.1-150. @article{2c1c508068cf4873947f22bd8f42f32e,title="Kidneydisease:Improvingglobaloutcomes(KDIGO)CKDworkgroup.KDIGO2012clinicalpracticeguidelinefortheevaluationandmanagementofchronickidneydisease",abstract="TheKidneyDisease:ImprovingGlobalOutcomes(KDIGO)2012ClinicalPracticeGuidelinefortheEvaluationandManagementofChronicKidneyDisease(CKD)servestoupdatethe2002KDOQIClinicalPracticeGuidelinesforChronicKidneyDisease:Evaluation,Classification,andStratificationfollowingadecadeoffocusedresearchandclinicalpracticeinCKD.Thedocumentaimstoprovidestate-of-the-artguidanceontheevaluation,managementandtreatmentforallpatientswithCKD.Specifically,theguidelineretainsthedefinitionofCKDbutpresentsanenhancedclassificationframeworkforCKD;elaboratesontheidentificationandprognosisofCKD;discussesthemanagementofprogressionandcomplicationsofCKD;andexpandsonthecontinuumofCKDcare:timingofspecialistreferral,ongoingmanagementofpeoplewithprogressiveCKD,timingoftheinitiationofdialysis,andfinallytheimplementationofatreatmentprogramwhichincludescomprehensiveconservativemanagement.Thedevelopmentoftheguidelinefollowedanexplicitprocessofevidencereviewandappraisal.Treatmentapproachesareaddressedineachchapterandguidelinerecommendationsarebasedonsystematicreviewsofrelevanttrials.Practicalcommentsorstatementswhichserveaseducationalpurposesareungraded,butincludedasimportantinformationforthereadership.AppraisalofthequalityoftheevidenceandthestrengthofrecommendationsfollowedtheGRADEapproach.Ongoingareasofcontroversies,limitationsoftheevidence,andinternationalrelevancearediscussedandadditionalsuggestionsareprovidedforfutureresearch.",keywords="Albuminuria,Chronickidneydisease,Classification,Clinicalpracticeguideline,Evidence-basedrecommendation,GFR,Glomerularfiltrationrate,KDIGO,Proteinuria,Systematicreview",author="AdeeraLevinandStevens,{PaulE.}andBilous,{RudyW.}andJosefCoreshand{DeFrancisco},{AngelL.M.}and{DeJong},{PaulE.}andGriffith,{KathrynE.}andHemmelgarn,{BrendaR.}andKunitoshiIsekiandLamb,{EdmundJ.}andLevey,{AndrewS.}andRiella,{MiguelC.}andShlipak,{MichaelG.}andHaiyanWangandWhite,{ColinT.}andWinearls,{ChristopherG.}",year="2013",month=jan,day="1",doi="10.1038/kisup.2012.73",language="English(US)",volume="3",pages="1--150",journal="KidneyInternationalSupplements",issn="2157-1724",publisher="NaturePublishingGroup",number="1",} 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