Glossary:Congenic Strain - Mouse Genome Informatics
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Congenic strains are derived by backcrossing to a parental inbred strain for at least ten generations while selecting for heterozygosity at a particular ... Home Genes Phenotypes HumanDisease Expression Recombinases Function Strains / SNPs Homology Tumors About Help FAQ Keywords,Symbols,orIDs(exactphrase) Keywords,Symbols,orIDs MouseLocation HumanLocation Search AllSearchTools Genes Genes&MarkersQuery BatchQuery JBrowseGenomeBrowser MultipleGenomeViewer(MGV) More Phenotypes Phenotypes,Alleles&DiseasesQuery MammalianPhenotype(MP)Browser HumanDisease(DO)Browser HumanPhenotype(HPO)Browser More HumanDisease Expression GeneExpressionDataSearch GeneExpressionLiteratureSearch MouseDevelopmentalAnatomyBrowser RNA-SeqandMicroarrayExperimentSearch More Recombinase(cre) Function GOBrowser Genes&MarkersQuery BatchQuery More Strains/SNPs StrainQuery SNPQuery MultipleGenomeViewer(MGV) More Homology Tumors SequenceSearches BLASTatNCBI JBrowseGenomeBrowser BatchQuery References ReferenceQuery GeneExpressionLiteratureQuery Vocabularies GOBrowser HumanDisease(DO)Browser MammalianPhenotype(MP)Browser MouseDevelopmentalAnatomyBrowser AdultMouseAnatomyBrowser HumanPhenotype(HPO)Browser BatchQuery MouseMine MouseGenomeBrowsers JBrowseGenomeBrowser MultipleGenomeViewer(MGV) Download AllMGIReports BatchQuery Genes&Markers SequenceData VertebrateHomology GeneOntologyData Strains&Polymorphisms GeneExpression PhenotypicData Recombinase(cre) Nomenclature References CloneCollections DNAMappingPanels MoreResources MoreResourcesIndex ResearchCommunityE-mailLists OnlineBooks NomenclatureHomePage MGIGlossary PrototypeTools MousePhenomeDatabase(MPD) DeltagenandLexiconKnockoutMice InternationalMousePhenotypingConsortium(IMPC) DecipheringtheMechanismsofDevelopmentalDisorders(DMDD) ContributedDataSets CommunityLinks MouseResources&ModelOrganismLinks Phenotypes&MutantsCommunityResources NucleicAcidsResearch(Journal)DatabaseSummary MouseFacts SoftwareDeveloperTools CreatingWebLinkstoMGI MouseMine DirectSQLAccount DatabaseSchemaBrowser AllMGIReports More SubmitData FindMice(IMSR) AnalysisTools Contact Us Browsers GlossaryTerm GlossaryTerm CongenicStrain MGIGlossary Definition Aninbredstrainofmousethatcontainsasmallgeneticregion(ideallyasinglegene)fromanotherstrain,butwhichisotherwiseidenticaltotheoriginalinbredstrain.Congenicstrainsarederivedbybackcrossingtoaparentalinbredstrainforatleasttengenerationswhileselectingforheterozygosityataparticularlocus.A.BY-H2bH2-T18b/SnJisacongenicstrain.SeealsotheRulesforNomenclatureofMouseandRatStrains. ContributingProjects: MouseGenomeDatabase (MGD),GeneExpressionDatabase (GXD),MouseModelsofHumanCancerdatabase(MMHCdb)(formerlyMouseTumorBiology (MTB),Gene Ontology (GO) CitingTheseResources FundingInformation WarrantyDisclaimer&CopyrightNotice Sendquestionsandcommentsto UserSupport. lastdatabaseupdate 03/22/2022 MGI6.18
延伸文章資訊
- 1Use of contiguous congenic strains in analyzing compound ...
A major technique for gene identification in such models utilizes series of congenic strains with...
- 2[Applications of congenic strains in the mouse] - PubMed
In the mouse, congenic strains are developed to introduce a chromosomal segment in a given inbred...
- 3Congenic Strain - an overview | ScienceDirect Topics
Congenic strains are created by the investigator to place a mutation onto different genetic backg...
- 4congenic strain
A congenic strain is an inbred strain that contains a small genetic region (ideally a single gene...
- 5Glossary:Congenic Strain - Mouse Genome Informatics
Congenic strains are derived by backcrossing to a parental inbred strain for at least ten generat...