congenic strain
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A congenic strain is an inbred strain that contains a small genetic region (ideally a single gene) from another strain, but which is otherwise identical to ... Skiptomaincontent OLS ExperimentalFactorOntology EFO EFO:0004003 Copy congenicstrain Gotoexternalpage http://www.ebi.ac.uk/efo/EFO_0004003 Copy Search Acongenicstrainisaninbredstrainthatcontainsasmallgeneticregion(ideallyasinglegene)fromanotherstrain,butwhichisotherwiseidenticaltotheoriginalinbredstrain.Congenicstrainsarederivedbybackcrossingtoaparentalinbredstrainforatleasttengenerationswhileselectingforretentionofaspecificlocusfromthedonorstrain.Forexample,CBACa.C3-KitW-x/JisaninbredstrainofCBA/CabackgroundontowhichtheKitW-xallelefromC3H/HeJhasbeenplaced. Synonyms: CON Treeview Term mappings Graphview Resettree Showallsiblings Preferredroot terms Allterms ThisisjusthereasatestbecauseIloseit Terminformation database crossreference NCIt:C14365 definitioncitation http://www.findmice.org/glossary.jsp termeditor HelenParkinson Termrelations Subclassof: inbredMusmusculusstrain has_qualitysomeinbred
延伸文章資訊
- 1Use of contiguous congenic strains in analyzing compound ...
A major technique for gene identification in such models utilizes series of congenic strains with...
- 2Glossary:Congenic Strain - Mouse Genome Informatics
Congenic strains are derived by backcrossing to a parental inbred strain for at least ten generat...
- 3Congenic Strain - an overview | ScienceDirect Topics
Congenic strains are created by the investigator to place a mutation onto different genetic backg...
- 4[Applications of congenic strains in the mouse] - PubMed
In the mouse, congenic strains are developed to introduce a chromosomal segment in a given inbred...
- 5第十三章實驗動物之遺傳和命名實驗動物之遺傳和命名
