過敏性氣喘| Allergy Insider
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氣喘是一種慢性肺病,會造成您的氣管腫脹、狹窄並產生過量黏液, 這些情況綜合起來,會導致難以呼吸。
氣喘嚴重而且普遍,全球約3 億人罹患此疾病。
... 對於其中一些人, ...
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Whatisallergicasthma?
Allergicasthma,orallergy-inducedasthma,isatypeofasthmathatistriggeredormadeworsebyallergies. Exposuretoallergens(e.g.,pollen,dander,mold,etc.)orirritantstowhichpatientsaresensitizedmayincreaseasthmasymptomsandprecipitateasthmaexacerbationsinpatientswhohaveasthma.1Asthmaandallergiesoftengohandinhand.Infact,upto90percentofchildrenand60percentofadultswithasthmasufferfromallergies.2,3
Asthma,thechronicandcomplexinflammatorydisorderthatnarrowstheairways,isaseriouspublichealthproblemthataffectsbothchildrenandadults. Approximately250,000peopleworldwidedieeachyearfromasthma,andalmostallofthesedeathsareavoidable.4
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AsthmaandAllergicTriggers:HowtoImproveAsthma
It’svitaltoidentifyunderlyingallergictriggers.Getanswerswithabloodtest.
CommonAllergicAsthmaCausesandTriggers
Manyofthesamesubstancesthatcancauseanallergicreactionmayalsoaffectpeoplewithasthma.Commonallergensthatmaytriggerallergicasthmainclude:
AnimalDander
DustMites
Insects
Pollen
Mold
Areyouahealthcareproviderlookingforacomprehensivelistofallergicasthmaallergensandassociatedsymptoms?
Exploreourfactsheets,an easilysharable,patient-friendlyresourcethatincludescrossreactivities,componentnames,andmanagementplans.
DiscoverAllergenFactSheets
AllergicAsthmaSymptoms
Asthmausuallypresentsasoneormoreofthefollowingsymptoms:4
Wheezing
Coughing
Shortnessofbreath
Chesttightness
Symptomsmayoccurinconnectionwithallergenexposure,exercise,coldair,dryair,andairwayinfections.Otherirritants,suchasstrongscentsorcigarettesmoke,mayalsotriggeranexacerbation.Tomanageallergicasthma,itisimportanttoidentifyandminimizeexposuretoallergictriggers.
Anasthmaattackmaybetriggeredbyexposuretoanallergen.Duringanasthmaattack,themusclesthatsurroundthebronchialtubesconstrict,narrowingtheairpassagesandmakingitextremelydifficulttobreathe.5Fortunately,almosteveryonewhoreceivestreatmentrecoversfromeventhemostsevereasthmaattacks.6
It’simportanttouncovertheallergensthatmayexacerbateasthmatoproperlymanageanddecreasetheriskofasthmaattacks.Seekemergencycareifexperiencingoneofthefollowingsymptoms:
· Difficultybreathing
· Severechestpain
· Difficultywalkingortalking
· Bluetinttotheskin
Learnabouttesting
Ithasbeenshownthatreducingexposuretoconfirmedallergytriggerscanhaveasignificantimpactontheabilitytocontrolasthmawithfewersymptoms,fewerhospitalvisits,andimprovedqualityoflife.7-9
FrequentlyAskedQuestionsAboutAllergiesandAsthma
Whatcausesasthma?
Mostpatientswithasthmahavemultipleallergicsensitizationscontributingtotheirallergenload.10,11Theseallergensensitizationscanaddtothepatient’striggerload,eventuallyresultinginasthmaexacerbations—evenfromother,non-allergic,triggers.10,12Forthosewithasthmaandaeroallergy(i.e.,anallergytoairbornesubstances,suchaspollenormoldspores),inadditiontopharmaceuticalstrategies,reducingexposuretosensitizedallergenscanalleviateorreducesymptoms.13-17
Theallergensymptomthresholdisthepointatwhichthecumulativeallergenloadleadstosymptoms.18,19Readmoreaboutthesymptomthreshold.
Whodevelopsasthma?
Anyone,regardlessofage,gender,race,orsocioeconomicstatuscanbeaffectedbyasthma.
Canasthmabecured?
Thereisnocureforasthma,soyourbestdefenseistolearnifyouhaveunderlyingtriggersandthenlimityourexposuretothem.Starttheconversationbygoingoveralistofyoursymptoms.Knowingthetypesofsymptomsexperiencedandwhentheyoccurcanhelpahealthcareproviderdetermineifyoumaybeacandidateforallergytesting.
Canreducingexposuretoallergictriggershelpasthma?
Yes.Reducingexposuretooneormoreallergictriggersmayhelpreducesymptoms.Thiscanonlybeaccomplishedbyworkingwithahealthcareprofessionaltounderstandyouruniqueallergyprofile.Starttheconversationbyfillingoutoursymptomtracker.
Isitpossibletooutgrowallergicasthma?
Unfortunately,itisnotpossibletooutgrowasthmaorforittogoaway.Asthmaisachronicdiseasethatpermanentlychangesyourlungs’airways.6 Itispossibleforsymptomsandattackstolessenorgetbetterovertime.However,theremayalwaysbeariskforthosesymptomstoreturn.
AllergicAsthmaTestingandManagement
Withallergicasthma,medicalhistoryisoftennotenoughtomakeanaccurateallergydiagnosis.Forexample,apatientcanpresentwithahistoryindicativeofhousedustmiteorcatallergybutactuallynotbesensitized.20Identifyingandreducingexposuretoallergenstowhichpatientsaresensitizedcanreducetheriskofinducedasthmaexacerbations,particularlyinthecaseofhousedustmitesensitization.1
Itisalsoimportanttoidentifyandtreatotherallergicconditions.Forexample,bothallergicrhinitisandnon-allergicrhinitis areriskfactorsforthedevelopmentofasthma.21Morethan80percentofpeoplewithasthmaalsosufferfromrhinitis, suggestingtheconceptof“oneairway,onedisease.”4Thepresenceofallergicrhinitiscommonlyexacerbatesasthma,increasingtheriskofasthmaattacks,emergencyvisits,andhospitalizationsforasthma.22-26
Abloodtest—togetherwith anallergy-focused medicalhistory—may helpidentifyunderlyingallergentriggers.
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FourQuestionstoAskaHealthcareProviderAboutAsthma
It’svitaltoidentifyunderlyingallergictriggers.
Getanswerswithabloodtest
Upto90percentofpatientsaresensitizedtomorethanoneallergen.11 Theeffectiscumulative:Apatientmayhaveanumberoftriggers,whichcombinedmayleadtosymptoms.7,12
PracticeParametersandGuidelinesforAllergicAsthma
Guidelinesrecommendfactorsthattriggerorexacerbateasthmabeidentifiedroutinelyanddocumentedinthemedicalrecordsandpersonalasthmaactionplansofallpatientswithasthma.27 Reducingexposuretooneormoreallergictriggerscanhelpreducesymptomsandtheneedformedication.28
Practiceparametershavebeendevelopedtoclassifyandmanagetreatmentofasthma,andguideline-directedmanagementhasbeenshowntoimprovediseasecontrol.29
Explorepracticeparametersandguidelines.
AttainingOptimalAsthmaControl-PracticeParameter-2005
Exercise-InducedBronchoconstriction-PracticeParameterUpdate-2016
DiagnosisandTreatmentofAsthma-PracticeParameter-1995
AllergicRhinitisandImpactonAsthma-Guidelines-2016
ManagementofAcuteLossofAsthmaControlintheYellowZone-PracticeParameter-2014
AlgorithmforDiagnosisandManagementofAsthma-PracticeParameterUpdate-1998
DiagnosisandTreatmentofAsthma-PracticeParameter-1995
Definition,Evaluation,andTreatmentofSevereAsthma-Guidelines-InternationalERS
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References
MurrayCS,FodenP,SumnerH,etal.PreventingSevereAsthmaExacerbationsinChildren.ARandomizedTrialofMite-ImpermeableBedcovers. AmJ Respir Crit CareMed. 2017;196(2):150-158.
Allen-RamneyF,SchoenwetterW,WeissT,etal.SensitizationtoCommonAllergensinAdultswithAsthma.JABFP.2005;(18)5434-439.
HostA,HalkenS.Practicalaspectsofallergy-testing.PaediatrRespirRev.2003;(4)312-318.
PawankarR,HolgateS,CanonicaG,atel.WorldAllergyOrganization.WhiteBookonAllergy(WAO).2011.http://www.worldallergy.org/UserFiles/file/WAO-White-Book-on-Allergy_web.pdf.AccessedDecember2017.
AmericanCollegeofAllergy,Asthma&Immunology,“AsthmaAttack,”https://acaai.org/asthma/symptoms/asthma-attack,accessedApril2020.
AmericanCollegeofAllergy,Asthma&Immunology,“Outgrowingasthma?”https://acaai.org/resources/connect/ask-allergist/outgrowing-asthma,accessedApril2020.
EgglestonPA.Controlofenvironmentalallergensasatherapeuticapproach.lmmunolAllergyClinNorthAm.2003;23(3):533-547.
MorganWJ,GruchallaR,KattanM,etal.ResultsofHome-BasedEnvironmentalInterventionamongUrbanChildrenwithAsthma.NEnglJMed.2004;351:1068-80.
HalkenS,HansenL,OSterballeO.Effectofmattressandpillowencasingsonchildrenwithasthmaandhousedustmiteallergy.JAllergyClinImmunol.2003;111:169-76.
EgglestonPA. Controlofenvironmentalallergensasatherapeuticapproach. lmmunol Allergy Clin NorthAm. 2003;23(3):533-547.
GiorgioCiprandi,CristoforoIncorvaia&FrancoFratiTheItalianStudyGrouponPolysensitization(2015)Managementofpolysensitizedpatient:frommoleculardiagnosticstobiomolecularimmunotherapy,ExpertReviewofClinicalImmunology,11:9,973-976,DOI:10.1586/1744666X.2015.1062365.
Wickman M. Whenallergiescomplicateallergies. Allergy. 2005;60(suppl 79):14-18.
Allen-RameyF, etal.JAmBoardFamPract. 2005;18(5):434-439.
HostA,HalkenS. Allergy. 2000;55:600-608.
MorganWJ,etal.N Engl JMed.2004;351:1068-80.
ZethraeusN, etal.ItalianJournalofPediatrics. 2010;36:61.
Janson, etal.JAllergyClinImmunol. 2009;123:840-6.
Duran-TauleriaE, Vignati G,GuedanMJ,etal.TheutilityofspecificimmunoglobulinEmeasurementsinprimarycare. Allergy. 2004;59(Suppl78):35-41.
NiggemannB,NilssonM,FriedrichsF. Paediatric allergydiagnosisinprimarycareisimprovedbyinvitroallergenspecific IgE testing. Pediatr AllergyImmunol. 2008;19:325-331.
SmithHE, HoggerC,LallemantC,etal.Isstructuredallergyhistorysufficientwhenassessingpatientswithasthmaandrhinitisingeneralpractice? JAllergyClinImmunol. 2009;123:646-650.
ScaddingGK, DurhamSR,MirakianR,etal.BSACIguidelinesforthemanagementofallergicandnon-allergicrhinitis. ClinExpAllergy. 2008;38:19-42.
Bousquet J,VanCauwenbergeP,KhaltaevN,etal.Allergicrhinitisanditsimpactonasthma. JAllergy Clin Immunol. 2001;108(suppl 5):S147-S334.
ThomasM,KocevarVS,ZhangQ,etal. Asthma-RelatedHealthCareResourceUseAmongAsthmaticChildren With andWithoutConcomitantAllergicRhinitis. Pediatrics. 2005;15:129-134.
PriceD,ZhangQ,KocevarVS,etal. Effectofaconcomitantdiagnosisofallergicrhinitisonasthma-relatedhealthcareusebyadults. Clin Exp Allergy. 2005;35:282-287.
Crystal-PetersJ,NeslusanC,CrownWH,etal.Treatingallergicrhinitisinpatientswithcomorbidasthma:theriskofasthma-relatedhospitalizationsandemergencydepartmentvisits. JAllergy Clin Immunol. 2002;109(1):57-62.
Valovirta E. ManagingCo-MorbidAsthma With AllergicRhinitis:TargetingtheOne-AirwayWithLeukotrieneReceptorAntagonists. WorldAllergyOrganJ. 2012;5:S210-S211.
NationalReviewofAsthmaDeaths(NRAD).WhyAsthmaStillKills:ConfidentialEnquiryReport.London:RCP;2014.
NIHGuidelinesfortheDiagnosisandManagementofAsthma,2007.
ShiffmanRNetal.BridgingtheGuidelineImplementationGap:ASystematic,Document-CenteredApproachtoGuidelineImplementation.JAmMedInformAssoc.2004;11:418–426.
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