C57BL/6J mouse (JAX™) | Animalab

Origin: The C57BL/6 mouse was developed by C.C. Little in 1921, after crossing the female N.57 with the male N.52 from a commercial breeding centre in the ... Animalab Products Animalmodels Mice C57BL/6Jmouse(JAX™) JAX C57BL/6Jmouse(JAX™) Code2498079-86 Generalmultipurposemodel,diet-inducedobesity,transgenic/knockoutmodeldevelopment,safetyandefficacytesting,immunology. Readmoreaboutproduct Getquote Tellacolleague GoogleScholar Seeotherproductsinapplications Immunology Metabolism Obesity,diabetes Aging Toxicology Transgenesis,targetedmutations Features Download Features Nomenclature:C57BL/6J Type:Inbredmice Origin:TheC57BL/6mousewasdevelopedbyC.C.Littlein1921,aftercrossingthefemaleN.57withthemaleN.52fromacommercialbreedingcentreintheUnitedStates(MissAbbyLathrop).ItwasintroducedintoTheJacksonLaboratoryin1948,atF22,thentoCharlesRiverLaboratoriesFrancein1981andUKin2004.BreedingisinaccordancewithTheJacksonLaboratorygeneticmanagementsystem.  C57BL/6Jisthemostwidelyusedinbredstrainandthefirsttohaveitsgenomesequenced.Althoughthisstrainisrefractorytomanytumors,itisapermissivebackgroundformaximalexpressionofmostmutations.C57BL/6Jmiceareresistanttoaudiogenicseizures,havearelativelylowbonedensity,anddevelopagerelatedhearingloss(thisstrainishomozygousfor Cdh23ahl).Theyarealsosusceptibletodiet-inducedobesity,type2diabetes,andatherosclerosis.Macrophagesfromthisstrainareresistanttotheeffectsofanthraxlethaltoxin. Coatcolor:Black Straincode: 632 Idealfor: Generalmultipurposemodel,diet-inducedobesity,transgenic/knockoutmodeldevelopment,safetyandefficacytesting,immunology JAX™StockNo:000664 Moreinformationaboutthestrain:  CharacteristicsofJAX™C57BL/6JMice MousePhenomeDatabase:C57BL/6J Note: OnlyTheJacksonLaboratoryandCharlesRiverinEuropeandJapanmaintaincoloniesofJAX™MicestrainswhicharederivedfrompedigreedmicefromTheJacksonLaboratoryandarere-infusedroutinelywithpedigreedmicetostabilisethegeneticintegrityandphenotypeofthesestrains. JAX™isa trademarkofTheJacksonLaboratoryregisteredintheUnitedStates.Allrightsreserved. CharlesRiverLaboratoriesistheofficialdistributorofJAXmiceinEurope.Clickandreadmore. Bredin: Germany,UK,France Healthreports: Usingstrainnomenclaturefindthestrainatlinksbelow animalshealthreportsbredinCharlesRiverGermany  animalshealthreportsbredinCharlesRiverUK  animalshealthreportsbredinCharlesRiverFrance   Note:WealsoofferC57BL/6Jmice withaSOPFhealthprofile. *PhotosprovidedcourtesyofCharlesRiver Download StrategiestominimizegeneticdriftandmaximizeexperimentalreproducibilityinmouseresearchpublicationEN Download ImportingspecialisedJAXstrainsthroughCharlesRiverEuropeEN Download AnimalpopularmodelsoverviewandqualityflyerEN,CRL,JAX Download Relatedproducts Steelco CageandrackwasherwithhingeddoorAC7500 Getquote KentScientific SomnoFlo™Low-flowelectronicvaporizer Getquote Altromin Breedingdietformiceandrats-RecipeCharlesRiver Getquote RWDLifeScience Stereotaxicanimalanesthesiasolutions Getquote Allentown NexGenIVC900formice Getquote