promoter | Learn Science at Scitable - Nature

Promoter sequences are DNA sequences that define where transcription of a gene by RNA polymerase begins. Promoter sequences are typically located directly ... Thispagehasbeenarchivedandisnolongerupdated   promoter   PromotersequencesareDNA sequencesthatdefinewheretranscriptionofagenebyRNApolymerasebegins. Promotersequencesaretypicallylocateddirectlyupstreamoratthe5'endof thetranscriptioninitiationsite.RNApolymeraseandthenecessary transcriptionfactorsbindtothepromotersequenceandinitiatetranscription. PromotersequencesdefinethedirectionoftranscriptionandindicatewhichDNA strandwillbetranscribed;thisstrandisknownasthesensestrand. Manyeukaryoticgeneshavea conservedpromotersequencecalledtheTATAbox,located25to35basepairs upstreamofthetranscriptionstartsite.Transcriptionfactorsbindtothe TATAboxandinitiatetheformationoftheRNApolymerasetranscription complex,whichpromotestranscription. FurtherExploration ConceptLinksforfurtherexploration cis-regulatoryelement | transcription | transcriptionfactor | enhancer | TATAbox | DNA | RNApolymerase | DNApolymerase | eukaryote | consensussequence RelatedConcepts (10) Genetics GeneInheritanceandTransmission GeneExpressionandRegulation NucleicAcidStructureandFunction ChromosomesandCytogenetics EvolutionaryGenetics PopulationandQuantitativeGenetics Genomics GenesandDisease GeneticsandSociety CellBiology CellOriginsandMetabolism ProteinsandGeneExpression SubcellularCompartments CellCommunication CellCycleandCellDivision ScientificCommunication CareerPlanning Loading... ScitableChat Register | SignIn