safeT21 Express - Femina Healthcare
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T21 Booking telephone: 23682333 ... 婦健醫療中心成立於2008年。
... safeT21, T21 Express $4900/$6500 (option of package with 20 weeks scan).
FeminaHealthcare
safeT21Express
四 維 超 聲 波 產 前 診 斷 中 心FeminaHealthcare 4DUltrasound,PrenatalDiagnosis&TreatmentCentre尖 沙 咀 堪 富 利 士 道 8 號 格 蘭 中 心 704-706 室 (尖 沙 咀 港 鐵 站 A2 出 口 ) Suite704-706,GrandCentre,8,HumphreyAvenue,TsimShaTsui(TST MTRA2Exit) 23682333
safeT21Express$4900
敏兒安T21
T21Booking telephone:23682333
Wearepanellistclinicforthe AmericanConsulate,AustralianConsulate&TeachersUnion.
Westrivetoensureyouhavea healthybaby. Wecare,weprovidevariousrangeofaccurateNIPTtosuityourneed.
FeminaHealthcareisestablishedin2008.Thecompanyhasservedmorethan100,000womensinceestablishment.Thevisionofthecompanyistoprovidegreatqualityhealthcareproductsandservices atreasonablepricetowomen.Thisvisionwillenablemanymorewomentoaffordgreatqualityhealthcareproductsandservices.婦健醫療中心成立於2008年。
自成立以來,該公司已為100,000多名婦女提供服務。
公司的願景是以合理的價格為女性提供優質的保健產品和服務。
這一願景將使更多婦女能夠負擔得起高質量的保健產品和服務。
Thereisnohiddencost(allinclusive,doctorfee,scan,bloodtestandlaboratoryfee),weDONOTchargeextra!
ALLbrandshavesameaccuracyforDownsyndrome.
NEWService:7weeksNIPT(earliestscreening);+screeningforpre-eclampsia(+$1000);SinglebloodtubeforNIPTand100genecarrierscreening
safeT21,T21Express$4900/$6500(optionofpackagewith20weeksscan).
safeT21express,NIFTYPROPlus,Panorama,FAEST,Harmony,Verifi(PreneticV)(From$2900onward!)
FurtherdiscountisavailableonMonday,FridayandSaturday.Wecanalsoprovidenuchaltranslucency(NT)screeningtogetherwithNIPT,packagewithmid-trimesterscan.
Femina offersmanydifferentNIPTpricefrom$2900andabove.Only$2900canguarantee thatyouwillnothaveDownsyndromebaby.
TheaccuracyfordetectingDownsyndromeandcommonchromosomeabnormalitiesarethesameforallbrands(extensiveresearchdone).
NuchalTranslucencyassessmentisessentialinfetalscreening.
RISKofDownsyndrome:20yearsold1in1000;30yearsold2in1000;40yearsold10in1000.
HowtochoosebetweenstandardsafeT21andAdvanceT21?
1.Foryoungmothers,Advancepanellikelytodetect2to3foldsmorechromosomalabnormalbabies.
2.ForAdvancepanel,youaremorelikelytodetectupto2to3casesofmicrodeletionsyndromeamong1000babies.
DoIneedNIPT?NIPTismoreaccurateandhaslessfalseresults.
NIPTdetects>99%ofDownsyndrome,comparedwithOSCAR85%.
2.HowtochoosethebestNIPTforme?
a)ForDownSyndrome:
IfonlyforDownsyndrome,Faest,Harmony,Panoramawillbesufficient.Cheaperbutasaccuratethanmorecomplexpanels.MostO&Gcolleges(AMCOG,RCOG&RANZCOG,SMFM)recommendscreeningforDownsyndromeandnotmicrodeletionsyndromes.
ALLBRANDShavethesameaccuracyfordetectingDownsyndrome(Allbrandsdetectionrate,accuracy>99%).
Cheapestbrandisnotdifferentfrommostexpensiveone.LikePradaandcheaphandbagcanalsohelpyoutocarryyourpersonalbelongings.
https://www.smfm.org/publications/193-cell-free-dna-screeninghttps://obgyn.onlinelibrary.wiley.com/doi/10.1002/pd.5216https://s3.amazonaws.com/cdn.smfm.org/publications/224/download-491f0e6962960848d2097447ab57a024.pdf
b)Forcommonmicrodeletionssyndrome(Notcommon,lessthan1in2000):
Mostcommonmicrodeletionis22q11(DiGeorgesyndrome,1in2000to4000,othersareveryrare)
StandardsafeT21,Panorama,orVerifi.
safeT21,Harmony&Verifidetect75%ofcommonmicrodeletionsyndromeandPanoramadetects>90%.
https://www.sciencedirect.com/science/article/pii/S0002937814023746
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5825123/
https://www.sciencedirect.com/science/article/pii/S1028455918302808
https://www.karger.com/Article/Fulltext/484317
Commonmicrodeletionsyndromesoccur1in2000babies.
3.Ifyouwantmostcomprehensive
safeT21Advancepanel,NIFTYPRO,GenesafeorVerifi-Extend.
safeT21advancepanelscreensformostconditions.
BEWARE:Allthesetestsarenotvalidates,thuslikelytohavehighfalsenegativeandfalsepositiveresults(wrongresults).
Overall1in100babiesmayhavenumbercopyvariants,NIPTcanscreenoutabout20=30%.
Comparisonofitems:Genesafecomplete>AdvancedsafeT21>NIFTYPRO>Verifi
4.Accuracyofsexdeterminationdependsonpanel
Harmony,Faest,safeT21,Panorama(>99.5%);Verifi&NIFTY(>98%).
FACTSaboutNIPT(s):
Not100%accurate.
ForDownsyndrome,allbrandscandetect>99%ofDownsyndrome
ForTrisomy13&18(Patau&Edwardsyndromes),differentbrandshavedifferentaccuracy.
NIPTtestsDNAfromchorionicvillus,andincountingmethod,alsotestsmothers’DNA.
Morecomplexpanelwillresultinmorefalsepositive,asitpicksupabnormalDNAfromplacentaandmothers(upto5/1000).
Abnormalresultneedstobeconfirmedbyinvasiveprenatalprocedure(i.e.amniocentesis).
NuchalTranslucency(NT)shouldbeassessed,asitcandetectotherfetalabnormalities.
Fetus/babywithNT>3.5mm,shouldhaveCVSoramniocentesis,riskofmicrodeletionisincreased.EvenadvancesafeT21canonlydetectlessthan30%ofmicrodeletionsyndromes.
Generalinformationofchromosomeabnormality:
1.RiskofDownsyndromeandcommonaneuploidydependonthemotherage.
A20yearsoldladyhas1in1000chanceofhavingDownsyndromebaby.Thisincreasesto1in300at30yearsoldand1in100at40yearsold.
2.Riskofmicrodeletiondoesnotchangewithpatientage.Overall1in100,butonlylessthan30%canbedetectedbyNIPT.
Mostcommonmicrodeletionis22q11(1in2000-4000cases).
3.Riskofsexchromosomeabnormalityisaround2-5in1000cases.
NIPTformicrodeletionsyndromes
MajorityofmicrodeletionandduplicationsyndromescannotbedetectedbyNIPT.Evenmostadvancedpanel(NIFTYPROorsafeT21)canonlydetectlessthan25%ofcopynumbervariants.Ifthereareindications,prenatalinvasivetestingshouldbeperformed.
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3351230/table/table1-0022155412440001/
AmericanCollegeofObstetricians&Gynecologists(ACOG),AmericanMedicalGeneticSociety,andSocietyofMaternalandFetalMedicineadviceAGAINSTscreeningformicrodeletionwithNIPT.UsingNIPTtoscreenformicrodeletionwillincreaseunnecessaryinvasivetestingwithverylowpositivepredictivevalue.Italsoprovidesfalsereassurance,aslessthan25%ofcopynumbervariantscanbedetected.
ACOG:“Routinecell-freeDNAscreeningformicrodeletionsyndromesshouldnotbeperformed.”
https://www.contemporaryobgyn.net/obstetrics/acog-guidelines-glance-screening-fetal-aneuploidy
https://journals.lww.com/greenjournal/Fulltext/2015/09000/Committee_Opinion_No__640__Cell_Free_Dna_Screening.51.aspx
4.Sexdetermination(gender)
Harmony,Faest,safeT21,Panorama(>99.5%);Verifi&NIFTY(>98%).
COMPANYINFORMATION
safeT21,Xcelom(subsidiaryof BerryGenomics,Beijing,China).
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