Leukotriene Receptor Antagonists (LTRA) - RESPe

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Leukotrienes are part of the complex inflammatory pathway of asthma. When activated, they cause bronchoconstriction and increase vascular permeability ... Skiptomaincontent Home Topics AboutRESPe Howtousethissite Linksandresources Contact LeukotrieneReceptorAntagonists(LTRA) Leukotrienesarepartofthecomplexinflammatorypathwayofasthma.Whenactivated,theycausebronchoconstrictionandincreasevascularpermeability(leakageoffluidoutofbloodvesselsintosurroundingtissues)causingswelling.Theyalsocauseincreasedmucusproduction.Allthesearefeaturesofpoorlycontrolledasthma. Leukotrieneantagonistsareconsidered‘addon’therapiestoinhaledasthmamedication.Ifsymptomsarestilltroublesomedespitepatientsbeingonmediumdoseinhalersteroidsandalongactingbronchodilator(LAMA). Theymaybeespeciallybeneficialfor nighttimesymptoms,iftherearenasalsymptoms(rhinitis)orhayfever.Theycanbehelpfulinexerciseinducedasthma. Drugname: Montelukast–Singulair. LTRAareavailableintabletsandaretakenatnight.Itcan betakenwithorafterfood. Itcantakeupto2weekstonoticeanybenefitsfromstartingLTRA. Aswithallmedicinesthereisariskofsideeffects.Commonsideeffectsarereportedasabdominalpain,headacheandthirst. Oftensideeffectscanlessenordisappearafter2-3weeks. ‹Xanthines up Steroids› Sitemap Contactus Login(adminonly) Disclaimer Accessibility Privacypolicy Copyright©2018-2022ChestHeart&StrokeScotlandandTheUniversityofEdinburgh.Somerightsreserved.SitepublishedbytheInteractiveContentTeam,InformationServices,TheUniversityofEdinburgh



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