Primary Aldosteronism | Hormone Health Network

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Primary aldosteronism (PA) is a type of aldosterone excess (hyperaldosteronism). This condition occurs when your adrenals, two small glands ... Home DiseasesandConditions PrimaryAldosteronism Moreinthissection WhatisEndocrinology? YourHealthandHormones DiseasesandConditions Seeall ThyroidOverview RareEndocrineGeneticDiseases PrimaryAldosteronism Support&Resources FindanEndocrinologist SHARE email facebook twitter pinterest print RelatedGlands AdrenalGlands RelatedHormones Aldosterone Whatisprimaryaldosteronism? Primaryaldosteronism(PA)isatypeofaldosterone excess(hyperaldosteronism).Thisconditionoccurswhenyouradrenals,twosmallglandslocatedonthetopofthekidney,producetoomuchofaldosterone.Aldosteroneisahormonethathelpsbalancethelevelsofsodium(salt)andpotassiuminyourbody.Havingtoomuchaldosteronecausesthebodytoholdontosodium,resultinginsaltandwaterbuild-upandariseinbloodpressure.Uncontrolledhighbloodpressurecanputyouatriskforstroke,heartattack,heartfailure,orkidneyfailure.TheriskofheartdiseaseandstrokemaybeevengreaterinpeoplewithPAthaninotherpeoplewithhighbloodpressure. Whentheincreaseofaldosteroneiscausedbyaprobleminyouradrenals,theconditioniscalledprimaryaldosteronism.Whentheproblemoriginatesoutsidetheadrenals,it’scalledsecondaryaldosteronism.ThemaincausesofPAare: Overactivityofbothadrenalglands,whichoccursinabouttwo-thirdsofcases Anoncancerousgrowthortumorinoneadrenalgland(alsocalledConn’ssyndrome),whichoccursinaboutone-thirdofcases Aninheriteddisorderwhichaffectsaldosteroneproduction,whichisrare  Acanceroustumoroftheadrenalgland,whichisextremelyrare Whataretheclinicalfeaturesforprimaryaldosteronism? Highbloodpressurethatrequiresmorethanthreemedicationstomanage Highbloodpressurethatstartedatayoungage(lessthanage30) Familyhistoryofstrokeatayoungage Lowpotassiumlevelinyourblood(calledhypokalemia) Howisprimaryaldosteronismdiagnosed? TodiagnosePA,yourdoctorwillmeasurethelevelsofaldosteroneandrenininyourblood.Reninisaproteinproducedbythekidneysthathelpsregulatebloodpressure.InPA,reninlevelsarelowandaldosteronelevelsarehigh.IfPAisdiagnosed,yourdoctorwillobtainanadrenalimagingstudy(usuallyCTorMRI)toseewhetheryoumighthaveonetumororbilateraladrenaltumors(onbothsides). Howisprimaryaldosteronismtreated? TreatmentofPAdependsonitscauseandcanincludemedicationorsurgery.Ifyouandyourdoctordecidetopursuesurgery,manytimesyourdoctorwillorderatestcalled"adrenalveinsampling",takingbloodsamplesfromeachadrenalveintomeasurealdosteroneandcortisol.Thistestwilldemonstratewhichadrenalgland(s)producesaldosteroneinexcess.Ifbothadrenalglandsareoveractive,treatmentwithmedicationandlifestylechangesisoftenpreferredoversurgery.Yourdoctormayprescribeaspecialtypeofdiuretic(“waterpill”)thatworkstoblocktheactionofaldosteroneinyourbody.Youwillalsoneedtolimitsodium(salt)inyourdiet. Whenonlyoneadrenalglandisoveractive,medicationandlifestylechangescantreatPA.However,doctorsusuallyrecommendsurgerytoremovetheculpritadrenalgland.Aftersurgery,youmaystillneedtotakemedication.Youshouldalsofollowahealthylifestyleby: Reducingsodiuminyourdiet Losingweight,ifneeded Exercisingregularly Limitingalcoholintake Stoppingsmoking Questionstoaskyourdoctor ShouldIbetestedtofindoutthecauseofmyhighbloodpressure? Whataremytreatmentoptions?  WhatkindofmedicationshouldItake?HowoftenshouldItakeit? HowlongwillIneedtotakemedication? Whatarethebenefitsandrisksofmymedication? HowoftenshouldIhavefollow-upappointments? ShouldIseeanendocrinologistformycare?  Editor(s): IrinaBancos,M.D.,MelanieSchorrHaines,M.D.,PaulStewart,M.D. LastUpdated: May2020 Citationinformation PrimaryAldosteronism-MayoClinic PrimaryAldosteronism-MedlinePlus Moreinthissection WhatisEndocrinology? YourHealthandHormones DiseasesandConditions Seeall ThyroidOverview RareEndocrineGeneticDiseases PrimaryAldosteronism Support&Resources FindanEndocrinologist FEATUREDRESOURCE FindanEndocrinologist Findanendocrinologisttodaytoensurethatyouareonthepathtohealthwiththerightmedicalcare. KeepYourBodyInBalance! PhysicianDirectory AboutthisContent TheHormoneHealthNetworkisthepubliceducationaffiliateoftheEndocrineSocietydedicatedtohelpingbothpatientsanddoctorsfindinformationontheprevention,treatmentandcureofhormone-relatedconditions. VisittheEndocrineSociety EnsuringtheQualityofourContent AllNetworkmaterials,includingthecontentonthissite,arereviewedbyexpertsinthefieldofendocrinologytoensurethemostbalanced,accurate,andrelevantinformationavailable.TheinformationonthissiteandNetworkpublicationsdonotreplacetheadviceofatrainedhealthcareprovider. Moreaboutourcontentpolicy AdvertisementsandSiteContent PaidadvertisementsappearontheHormoneHealthNetwork.Advertisingparticipationdoesnotinfluenceeditorialdecisionsorcontent. TermsandPolicies Backtotop Signup



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