自體免疫疾病| Allergy & Autoimmune Disease - Thermo Fisher
文章推薦指數: 80 %
... 種不同的自體免疫疾病。
儘管被視為罕見疾病,自體免疫疾病仍影響了高達8% 的人口。
1 ... 診斷和治療是幫助患者管理各種自體免疫疾病症狀的關鍵,而這類疾病包括:.
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AutoimmuneDiseases
UnderstandingAutoimmuneDisease
Currentlytherearemorethan120differentautoimmunediseases.Althoughperceivedasrare,autoimmunediseasesaffectupto8percentofthepopulation.1
About AutoimmuneDisease
Frequentlythesediseases,whenundiagnosedanduntreated,areassociatedwithapoorprognosisforthepatient.Inmanyautoimmunediseases,particularlyearlyinthediseasecourse—whenitismostmodifiable—patientsoftenpresentwithoverlappingclinicalfeatures,makingdiagnosisbysymptomsalonenearlyimpossible.1
Usingclinicaldiagnosticsfromyourlocalpathologylaboratorytolookbeneaththesurfaceinthisclinicallychallengingfieldcanprovidekeydiagnosticcluestoaidyourdifferentialdiagnosis.Thiscanmeanthatyourpatientisdiagnosedsoonerinthecourseoftheirdiseaseandreceivetreatmentthatcanpotentiallyhaveasignificantimpactonprognosis.
Diagnosisandtreatmentiskeytohelpingpatientsmanagesymptomsforarangeofautoimmunediseases,whichinclude:
AntiphospholipidSyndrome(APS)
ConnectiveTissueDiseases(CTD)
GastrointestinalDisease(GI)
RheumatoidArthritis(RA)
ThyroidDisease
Vasculitis
ExploreTypesofAutoimmuneDisease
APS
CTD
GIDisease
Gastro
RA
RA
ThyroidDisease
Vasculitis
Thyroid
Vasculitis
75%ofpeoplewithautoimmunediseasearewomen.3
Whileautoimmunediseasesaffectmillionsofpeopleworldwide,womenaremoreatrisk.
Autoimmunediseasesinwomen:Athreattowomen2
Datahighlightsthatgenderbiastowardfemalesishigh(9:1)3inthemajorityofautoimmunediseases,andprevalencecanbeespeciallyhighincertaindiseases,suchasthyroiddiseases,systemiclupuserythematosus(SLE),andSjögren’s syndrome.Thesediseasesalsodominatethelistofthetop10leadingcausesofdeathamongwomen.4
Dependingontheautoantibodyinvolved,autoimmunediseasescanmanifestthemselvesandbeclassifiedaseitherorganspecificorsystemic.
Thespectrumofautoimmunediseases
Organ-specificdiseasesexamplesinclude:
Hashimoto’sthyroiditis
Celiacdisease(CD)
Inflammatoryboweldisease(IBD)
Systemicdiseasesexamplesinclude:
Rheumatoidarthritis(RA)
Sjögren’sSyndrome
Systemiclupuserythematosus(SLE)
Vasculitis
Inmanyautoimmunediseases,patientsoftenpresentwithoverlappingclinicalfeatures, makingdifferentialdiagnosisbysymptomsalonenearlyimpossible.1
LearnmoreaboutspecificAIdiseases
AutoimmuneDisease
Learnabouttestingforautoimmunediseases
TestingOptions
References
ProgressinAutoimmuneDiseaseResearch.NationalInstituteofHealth,AutoimmuneDiseaseCoordinatingCommittee.2005,www.niaid.nih.gov/sites/default/files/adccfinal.pdf.AccessedDecember2017.
AutoimmuneDiseaseResearchCenterattheJohnsHopkinsMedicalInstitutions.BroadSpectrumofAutoImmuneDisease.http://autoimmune.pathology.jhmi.edu/whatis_spectrum.cfm.AccessedOctober2017.
Ngo,ST,SteynFJ,McCombePA.GenderDifferencesinAutoimmuneDisease.FrontiersinNeuroendocrinology.2014;347-369.www.sciencedirect.com/science/article/pii/S0091302214000466#s0180.AccessedOctober2017.
Walsh,SJ,RauLM. AutoimmuneDiseases:ALeadingCauseofDeathamongYoungandMiddle-AgedWomenintheUnitedStates. AmJPublicHealth. 2000;90:1463-1465.
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