Lumpectomy - Wikipedia

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Lumpectomy is a surgical removal of a discrete portion or "lump" of breast tissue, usually in the treatment of a malignant tumor or breast cancer. Lumpectomy FromWikipedia,thefreeencyclopedia Jumptonavigation Jumptosearch Thisarticleneedsmoremedicalreferencesforverificationorreliestooheavilyonprimarysources.Pleasereviewthecontentsofthearticleandaddtheappropriatereferencesifyoucan.Unsourcedorpoorlysourcedmaterialmaybechallengedandremoved.Findsources: "Lumpectomy" – news ·newspapers ·books ·scholar ·JSTOR(January2022) LumpectomyLumpectomyandaxillarydissectionperformedthroughoneincisionOthernamesPartialmastectomyICD-9-CM85.21MeSHD015412[editonWikidata] Lumpectomy(sometimesknownasatylectomy,partialmastectomy,breastsegmentalresectionorbreastwidelocalexcision)isasurgicalremovalofadiscreteportionor"lump"ofbreasttissue,usuallyinthetreatmentofamalignanttumororbreastcancer.[1]Itisconsideredaviablebreastconservationtherapy,astheamountoftissueremovedislimitedcomparedtoafull-breastmastectomy,andthusmayhavephysicalandemotionaladvantagesovermoredisfiguringtreatment.Sometimesalumpectomymaybeusedtoeitherconfirmorruleoutthatcancerhasactuallybeendetected.Alumpectomyisusuallyrecommendedtopatientswhosecancerhasbeendetectedearlyandwhodonothaveenlargedtumors.Althoughalumpectomyisusedtoallowformostofthebreasttoremainintact,theproceduremayresultinadverseaffectsthatcanincludesensitivityandresultinscartissue,pain,andpossibledisfigurationofthebreastifthelumptakenoutissignificant.[2]AccordingtoNationalComprehensiveCancerNetworkguidelines,lumpectomymaybeperformedforductalcarcinomainsitu(DCIS),invasiveductalcarcinoma,orotherconditions.[3] Contents 1Examplesofcancerstreated 2Procedure 3Seealso 4References 5Externallinks Examplesofcancerstreated[edit] DCIS,orintraductalcarcinoma,isbydefinitionabreastcancerthatislimitedtotheliningofthemilkducts,[4]andaccountsforabout20%ofbreastcancerintheUS.[5]AlthoughearlytreatmentofDCISwassimilartoinvasivebreastcancer,involvingfullmastectomyandsometimeslymphnodedissection,anevolutioninunderstandingaboutthedifferentkindsofbreastcancerpromptedinvestigationsintotheadequacyoflessextremesurgicaltreatments.Theresultsofaneight-yearrandomizedclinicaltrialinthelate1980sshowedthat,althoughlumpectomyalonewasassociatedwithsignificantrecurrence,lumpectomywithlocalradiationtherapyachievedsimilaroutcomestototalmastectomyintreatmentofDCIS.[6]Thiswasthefirstsubstantialdatathatshowedthatso-called"breastconservingtherapy"wasarealpossibility. AfteralumpectomyisperformedforDCIS,localradiationtherapyistypicallyperformedtohelpeliminatemicroscopic-leveldisease.Axillarysentinellymphnodebiopsy,asamethodofscreeningformetastaticdiseaseinotherwisenon-invasiveDCIS,isfallingoutoffavorbecausetherisksofprocedureoutweighanyeffectonoutcomes.[7]ForDCIS,chemotherapyisnotrecommended,buttamoxifenmayberecommendedfortumorswhichcontainanabundanceofestrogenreceptors.[8] Forpatientswithinvasiveductalcarcinomawhohavelumpectomies,lymphnodebiopsyandradiationtherapyareusuallyrecommended.Adjuvantchemotherapyisoftenrecommended,butitmaynotberecommendedifthetumorissmallandtherearenolymphnodemetastases.Forlargertumors,neoadjuvantchemotherapymayberecommended. Procedure[edit] Alumpectomyisasurgerytoremoveabreasttumoralongwitharesectionmarginofnormalbreasttissue.Themarginisthehealthy,noncanceroustissuethatisnexttothetumor.Apathologistanalyzesthemarginexcisedbythelumpectomytodetectanypossiblecancercells.Acancerousmarginis"positive",whileahealthymarginis"clean"or"negative".Are-excisionlumpectomyisperformedifthemarginisdetectedtobepositiveorcancerouscellsareveryclosetothemargin.[9]Sentinellymphnodebiopsy(SLNB)oraxillarylymphnodedissection(ALND)maybeusedtodetermineifthecancerhasprogressedawayfromthebreastandintootherpartsofthebody.[10]Sentinellymphnodebiopsyistheanalysisofafewremovedsentinelnodesforthepresenceofcancerouscells.Aradioactivesubstanceisusedtodyethesentinelnodesforeasyidentificationandremoval.[2]Ifcancerisdetectedinthesentinelnodethenfurthertreatmentisneeded.Axillarynodedissectioninvolvestheexcisionoflymphnodesconnectedtothetumorbythearmpit(axilla).Radiationisusuallyusedinconjunctionwiththelumpectomytopreventrecurrence.[11]Theradiationtreatmentcanlastfivetosevenweeksfollowingthelumpectomy.Althoughthelumpectomywithradiationhelpstodecreasetheriskofthecancerreturning(localrecurrence);itdoesnotprolongsurvival;itisnotacure,andcancermaystillcomeback.However,localrecurrences(confinedtothebreastarea)afterlumpectomycanbetreatedeffectivelywithmastectomy,andthesewomenwerestilldisease-free20yearsaftertheiroriginallumpectomiesandrecurrencetreatments.[12] Seealso[edit] Listofsurgeriesbytype BernardFisher(scientist) References[edit] ^"Breastlumpremoval:MedlinePlusMedicalEncyclopedia".medlineplus.gov.Retrieved2018-11-07. ^ab"Lumpectomy-MayoClinic".Mayoclinic.org.Retrieved19April2018. ^"Lumpectomy".Desertsurgical.com.Retrieved19March2013. ^"DuctalCarcinomaInSitu(DCIS)".PubMedHealthGlossary. ^DeSantisC,SiegelR,BandiP,JemalA(2011)."Breastcancerstatistics,2011".CA:ACancerJournalforClinicians.61(6):409–18.doi:10.3322/caac.20134.PMID 21969133.S2CID 207727461. ^FisherB,RedmondC,PoissonR,MargoleseR,WolmarkN,WickerhamL,FisherE,DeutschM,CaplanR,PilchY(March1989)."Eight-yearresultsofarandomizedclinicaltrialcomparingtotalmastectomyandlumpectomywithorwithoutirradiationinthetreatmentofbreastcancer".TheNewEnglandJournalofMedicine.320(13):822–8.doi:10.1056/nejm198903303201302.PMID 2927449. ^ZujewskiJ,Eng-WongJ(August2005)."Sentinellymphnodebiopsyinthemanagementofductalcarcinomainsitu".ClinicalBreastCancer.6(3):216–22.doi:10.3816/cbc.2005.n.023.PMID 16137431. ^"Ductalcarcinomainsitu".Getglue.com.Retrieved19March2013. ^"About20%ofWomenNeedMoreSurgeryAfterLumpectomy".Breastcancer.org.2015-02-05.Retrieved19April2018. ^"SurgeryforBreastCancer".Cancer.org.Retrieved19April2018. ^FisherB,AndersonS,BryantJ,MargoleseRG,DeutschM,FisherER,JeongJH,WolmarkN(October2002)."Twenty-yearfollow-upofarandomizedtrialcomparingtotalmastectomy,lumpectomy,andlumpectomyplusirradiationforthetreatmentofinvasivebreastcancer".TheNewEnglandJournalofMedicine.347(16):1233–41.doi:10.1056/NEJMoa022152.PMID 12393820.S2CID 4634763. ^"LumpectomyPlusRadiation".Breastcancer.org.2015-03-04.Retrieved19April2018. Externallinks[edit] Lumpectomy:WhattoExpect,19March2013 BreastLumpRemoval:MedlinePlusEncyclopedia,7November2018 vteTestsandproceduresinvolvingthebreastBreastsurgery Breast-conservingsurgery Lumpectomy Mastectomy Radicalmastectomy Mammaplasty Breastimplant Breastreduction SPAIR Mastopexy Breastreconstruction InterventionsontheLactiferousducts Ductallavage Ductoscopy Microdochectomy Centralductexcision Breastimaging Mammography Positronemissionmammography Tomosynthesis Xeromammography Galactography BreastMRI Breastultrasound Automatedwhole-breastultrasound Scintimammography Elastography Other Breastbiopsy Fine-needleaspiration Breastcancerscreening Breastself-examination Ductallavage Retrievedfrom"https://en.wikipedia.org/w/index.php?title=Lumpectomy&oldid=1093419331" Categories:BreastsurgeryObstetricalandgynaecologicalproceduresSurgicaloncologySurgicalremovalproceduresHiddencategories:ArticlesneedingadditionalmedicalreferencesfromJanuary2022AllarticlesneedingadditionalreferencesArticlesrequiringreliablemedicalsources Navigationmenu Personaltools NotloggedinTalkContributionsCreateaccountLogin Namespaces ArticleTalk English Views ReadEditViewhistory More Search Navigation MainpageContentsCurrenteventsRandomarticleAboutWikipediaContactusDonate Contribute HelpLearntoeditCommunityportalRecentchangesUploadfile Tools WhatlinkshereRelatedchangesUploadfileSpecialpagesPermanentlinkPageinformationCitethispageWikidataitem Print/export DownloadasPDFPrintableversion Inotherprojects WikimediaCommons Languages العربيةDeutschEspañolفارسیGalegoItalianoNederlandsPortuguêsРусскийСрпски/srpski Editlinks

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