Upstream and downstream (DNA) - Wikipedia
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By convention, upstream and downstream relate to the 5' to 3' direction respectively in which RNA transcription takes place. Upstream is toward the 5' end of ... Upstreamanddownstream(DNA) FromWikipedia,thefreeencyclopedia Jumptonavigation Jumptosearch Termsmeaningrelativetothedirectionthattranscriptiontakesplace Seealso:Directionality(molecularbiology) Inmolecularbiologyandgenetics,upstreamanddownstreambothrefertorelativepositionsofgeneticcodeinDNAorRNA.EachstrandofDNAorRNAhasa5'endanda3'end,sonamedforthecarbonpositiononthedeoxyribose(orribose)ring.Byconvention,upstreamanddownstreamrelatetothe5'to3'directionrespectivelyinwhichRNAtranscriptiontakesplace.[1]Upstreamistowardthe5'endoftheRNAmoleculeanddownstreamistowardthe3'end.Whenconsideringdouble-strandedDNA,upstreamistowardthe5'endofthecodingstrandforthegeneinquestionanddownstreamistowardthe3'end.Duetotheanti-parallelnatureofDNA,thismeansthe3'endofthetemplatestrandisupstreamofthegeneandthe5'endisdownstream. SomegenesonthesameDNAmoleculemaybetranscribedinoppositedirections.Thismeanstheupstreamanddownstreamareasofthemoleculemaychangedependingonwhichgeneisusedasthereference. Seealso[edit] Upstreamanddownstream(transduction) References[edit] ^HarveyLodish(2008).MolecularCellBiology.W.H.Freeman.pp. 286–.ISBN 978-0-7167-7601-7. Thismolecularbiologyarticleisastub.YoucanhelpWikipediabyexpandingit.vte Retrievedfrom"https://en.wikipedia.org/w/index.php?title=Upstream_and_downstream_(DNA)&oldid=1024758005" Categories:MolecularbiologyOrientation(geometry)MolecularbiologystubsHiddencategories:ArticleswithshortdescriptionShortdescriptionmatchesWikidataAllstubarticles Navigationmenu Personaltools NotloggedinTalkContributionsCreateaccountLogin Namespaces ArticleTalk English Views ReadEditViewhistory More Search Navigation MainpageContentsCurrenteventsRandomarticleAboutWikipediaContactusDonate Contribute HelpLearntoeditCommunityportalRecentchangesUploadfile Tools WhatlinkshereRelatedchangesUploadfileSpecialpagesPermanentlinkPageinformationCitethispageWikidataitem Print/export DownloadasPDFPrintableversion Languages العربيةBosanskiDeutschفارسیBahasaIndonesiaPortuguêsTürkçe Editlinks
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