Primary aldosteronism reviewPrimary hyperaldosteronism LancetAldosteronism diagnosisPrimary aldosteronism guidelinePrimary Aldosteronism (Conn's Syndrome) - Cleveland Clinic
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Primary aldosteronism (also called Conn's syndrome) is a rare condition caused by overproduction of the hormone aldosterone that controls ... ComingtoaClevelandCliniclocation?Visitation,maskrequirementsandCOVID-19information Home / HealthLibrary / Disease&Conditions PrimaryAldosteronism(Conn'sSyndrome) Primaryaldosteronism(alsocalledConn’ssyndrome)isarareconditioncausedbyoverproductionofthehormonealdosteronethatcontrolssodiumandpotassiumintheblood.Theconditionistreatedwithmedicationsandlifestylechangestocontrolbloodpressure,andinsomecasessurgery. Appointments216.444.6568 Appointments&Locations ContactUs Overview SymptomsandCauses DiagnosisandTests ManagementandTreatment Prevention Outlook/Prognosis PrimaryAldosteronism(Conn'sSyndrome) Overview SymptomsandCauses DiagnosisandTests ManagementandTreatment Prevention Outlook/Prognosis BackToTop Overview Adrenalglandlocatedonthetopofeachkidney. Whatisprimaryaldosteronism(Conn’ssyndrome)? Primaryaldosteronismmeanstheadrenalglandsproducetoomuchofthesteroidhormonealdosterone,whichhelpscontrolsodiumandpotassiumexcretion.Theadrenalglandsaretwosmalltriangularglands,oneontopofeachkidney. Thiscondition,alsocalledConn’ssyndrome,resultsfromoverproductionofaldosteronebyoneorbothadrenalglands.Overproductionofaldosteronebybothglands,noncancerousmassesinoneadrenalglandor,veryrarely,canceroustumors,cancauseoverproductionofaldosterone. Primaryaldosteronismusuallymanifestswithhighbloodpressureandlowpotassiumlevelsintheblood.Leftunchecked,highbloodpressureraisesyourriskforcomplicationsincludingheartattackandstroke,whilelowpotassiumcancauseheartrhythmirregularities. Whoislikelytohaveprimaryaldosteronism(Conn’ssyndrome)? Anyonecandevelopprimaryaldosteronism.Butit’smorelikelytobepresentifyouhave: Lowbloodpotassiumlevels(hypokalemia). Highbloodpressurestartingbeforeage30. Highbloodpressurerequiringthreeormoremedicationstomanage. Anadrenalmass. SymptomsandCauses Whatcausesprimaryaldosteronism(Conn’ssyndrome)? Primaryaldosteronismresultsfromoverproductionofaldosteronebytheadrenalglandsthemselves.Thishormonehelpsregulatethebody’sbalanceofwaterandsodium(salt),bloodvolumeandbloodpressure. Insomecases,primaryaldosteronismresultsfrombenign,ornoncancerous,tumorsinoneorbothadrenalglands. Rarely,primaryaldosteronismoccursbecauseofaninheriteddisorder.Inextremelyrarecases,canceroustumorsinoneorbothadrenalglandscauseprimaryaldosteronism. Whatarethesymptomsofprimaryaldosteronism(Conn’ssyndrome)? Primaryaldosteronismgenerallycauseshighbloodpressurewithlowpotassium. Othersymptomsmayinclude: Excessivethirst. Fatigue. Frequenturination. Headache. Musclecramps. Visualdisturbances. Weaknessortingling. DiagnosisandTests Howisprimaryaldosteronism(Conn’ssyndrome)diagnosed? Doctorsdiagnoseprimaryaldosteronismbymeasuringthelevelsofhormoneslikealdosteroneandreninalongwithelectrolytes,includingsodiumandpotassiuminpatientswithhighbloodpressure.Electrolytesaremineralsthathelpbalancetheamountofwaterinyourbody. Yourhealthcareprovidermayrecommendfurthertestingtoruleoutadrenalglandtumors.Thesemayinclude: Computerizedtomography(CT)scan,whichusesX-raystocreatepicturesofinternalbodystructures. Magneticresonanceimaging(MRI)usingradiowavesandhigh-poweredmagnetstovisualizetheinsideofyourbody. ManagementandTreatment Howisprimaryaldosteronism(Conn’ssyndrome)treated? Iftheextraaldosteroneisproducedbybothadrenalglandsitisusuallytreatedwithmedicationslikespirinolacone(brandnameAldactone®)oreplerenone(Inspra®)whichblocktheeffectsofaldosterone.Ifitisproducedbyoneadrenalgland,removingthatglandisanalternativetothosemedications. Yourdoctormayalsorecommendlifestylechanges,including: Frequentexercise. Limitingalcoholintake. Reducingsodiuminyourdiet. Stoppingsmoking. Whatcomplicationsareassociatedwithprimaryaldosteronism(Conn’ssyndrome)? Ifyoudon’ttreatprimaryaldosteronismyourbloodpressuremayincreasetodangerouslevels.Italsodisruptsthebalanceofelectrolytesinthebody. Electrolyteimbalancesandprolongedhighbloodpressureincreaseyourriskforseriouscomplications,including: Heartattackorheartfailure. Irregularheartbeat. Kidneyfailure. Stroke. Temporaryparalysis,ortheinabilitytomove. Prevention Canprimaryaldosteronism(Conn’ssyndrome)beprevented? Thereisnowaytopreventprimaryaldosteronism.Monitoringyourbloodpressurefrequentlycanhelpspotproblems. Outlook/Prognosis Whatistheprognosis(outlook)forpeoplewithprimaryaldosteronism(Conn’ssyndrome)? Patientswithprimaryaldosteronismcanbemanagedwithmedications.Ifthealdosteroneiscomingfromatumorinoneglandtheycanpotentiallybecuredbysurgerytoremoveadrenalglandtumors. 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延伸文章資訊
- 1Conn's syndrome - Healthdirect
Conn's syndrome is a hormonal condition in which one or both adrenal glands produce more of the h...
- 2Conn Syndrome: What Is It, Causes, Symptoms ... - Osmosis
Conn syndrome, also known as primary hyperaldosteronism, refers to the excessive secretion of the...
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2. 康氏症(Conn's syndrome) 康氏症是因腎上腺皮質另一類荷爾蒙分泌細胞不正常之增生分泌醛固酮所致，也稱為原發性醛固酮症(Primary Aldosteronism)，會造成血中...
- 4原發性高醛固酮症 - 维基百科
原發性高醛固酮症（Primary aldosteronism），又稱康氏症（Conn's syndrome），是腎上腺生產過量醛固酮而造成腎素水平下降而导致的一种疾病，通常症狀不嚴重。
- 5Conn Syndrome - StatPearls - NCBI Bookshelf
Conn syndrome was named after J. W. Conn who first described it in 1955, in a patient who had hyp...
