Estrogen's Effects on the Female Body - Johns Hopkins ...

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Estrogens are a group of hormones that play an important role in the normal sexual and reproductive development in women. They are also sex hormones. The ... SkipNavigation COVID-19Updates Masksarerequiredinsideallofourcarefacilities.Wearevaccinatingalleligiblepatients.Learnmore: Vaccines,Boosters&AdditionalDoses|Testing|PatientCare|VisitorGuidelines|Coronavirus|EmailAlertsFindmoreCOVID-19testinglocationsonMaryland.gov. HealthHome ConditionsandDiseases Estrogen'sEffectsontheFemaleBody ShareonFacebook ShareonTwitter ShareonLinkedin ShareonPinterest ShareviaEmail PrintthisPage Whatisestrogen? Estrogensareagroupofhormonesthatplayanimportantroleinthenormalsexualandreproductivedevelopmentinwomen.Theyarealsosexhormones.Thewoman'sovariesmakemostestrogenhormones,althoughtheadrenalglandsandfatcellsalsomakesmallamountsofthehormones. Inadditiontoregulatingthemenstrualcycle,estrogenaffectsthereproductivetract,theurinarytract,theheartandbloodvessels,bones,breasts,skin,hair,mucousmembranes,pelvicmuscles,andthebrain.Secondarysexualcharacteristics,suchaspubicandarmpithair,alsostarttogrowwhenestrogenlevelsrise.Manyorgansystems,includingthemusculoskeletalandcardiovascularsystems,andthebrainareaffectedbyestrogen. Hormonereplacementtherapyupdate Tolearnmoreaboutwomen'shealth,andspecificallyhormonereplacementtherapy,theNationalHeart,Lung,andBloodInstituteoftheNationalInstitutesofHealth(NIH)startedalargestudyin1991.ItwascalledtheWomen'sHealthInitiative(WHI).Thehormonetrialhadtwostudies:theestrogen-plus-progestin(HRT)studyofwomenwithauterusandtheestrogen-alone(ERT)studyofwomenwithoutauterus.Bothstudieswereconcludedearlywhentheresearchshowedthathormonereplacementdidnothelppreventheartdiseaseanditincreasedriskforsomemedicalproblems. TheFDAstatesthathormonetherapyshouldnotbetakentopreventheartdisease. Theseproductsareapprovedtherapiesforrelieffrommoderatetoseverehotflashesandsymptomsofvaginaldryness.Althoughhormonetherapymayhelppreventosteoporosis,itshouldonlybeconsideredforwomenathighriskofosteoporosiswhocannottakenon-estrogenmedicines.TheFDArecommendshormonetherapybeusedatthelowestdosesfortheshortestdurationneededtoachievetreatmentgoals.Postmenopausalwomenwhouseorareconsideringusinghormonetherapyshoulddiscussthepossiblebenefitsandriskstothemwiththeirhealthcareprovider. TheNationalHeart,Lung,andBloodInstituteoffersthefollowingsuggestionsforwomenwhoaredecidingwhetherornottousepostmenopausalhormonetherapy: Themostimportantthingawomancandoindecidingtocontinuehormonereplacementtherapyisdiscussthecurrentresearchwithherhealthcareproviderandhealthcareteam. Womenneedtobeawarethattakingacombinedprogesteroneandestrogenregimenorestrogenaloneisnolongerrecommendedtopreventheartdisease.Awomanshoulddiscussotheralternativesofprotectingtheheartwithherhealthcareprovider. Womenshoulddiscusswiththeirhealthcareprovidersthevalueoftakingcombinedprogesteroneandestrogenreplacementtherapyorestrogentopreventosteoporosis.Theremaybealternativetreatmentsbasedonawoman'shealthprofile. Alwaysseeyourhealthcareproviderformoreinformation. FindaTreatmentCenter FindAdditionalTreatmentCentersat: HowardCountyGeneralHospital SibleyMemorialHospital SuburbanHospital RequestanAppointment FindaDoctor 410-955-5000 Maryland 855-695-4872 OutsideofMaryland +1-410-502-7683 International FindaDoctor SeeMore



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